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Post-traumatic headache due to mild traumatic brain injury: Current knowledge and future directions
1Mayo Clinic, Department of Neurology, Phoenix, AZ, USA.
Cephalalgia : an International Journal of Headache
|November 19, 2020
Summary
Post-traumatic headache is a common persistent symptom after mild traumatic brain injury. Further research is needed to refine diagnosis, understand causes, and develop effective treatments for this condition.
Area of Science:
- Neurology
- Traumatology
Background:
- Post-traumatic headache (PTH) is a frequent and enduring consequence of mild traumatic brain injury (mTBI).
- Understanding PTH is crucial for managing mTBI patients effectively.
Purpose of the Study:
- To review current knowledge on diagnostic criteria, clinical presentation, epidemiology, pathophysiology, and treatment of PTH.
- To identify key areas for future research in PTH.
Main Methods:
- This study is a narrative review of existing literature on PTH following mTBI.
Main Results:
- Diagnostic criteria for PTH require headache onset within 7 days of injury.
- While many PTH cases resolve quickly, 30-50% persist beyond 3 months.
- Pathophysiology involves structural, functional, metabolic, and neuroinflammatory changes, but evidence quality for treatment is limited.
Conclusions:
- Significant progress has been made, but research priorities include optimizing diagnostic criteria.
- Further understanding of PTH pathophysiology and predictors of persistence is needed.
- Developing safe and effective therapies for PTH remains a critical goal.
