[Neuropsychiatric complications of COVID-19]

The COVID-19 coronavirus pandemic is a major stressor in the population, due to our physical vulnerability, our fear of dying, the major upheaval of our life habits linked to confinement and the difficulty of projecting us into the future. Caregivers themselves are more exposed than ever to burnout and post-traumatic stress disorder. However, other neuropsychiatric complications related directly to the viral infection of the central nervous system or secondary to the immune storm are to be feared in the short term (encephalopathies, myopathies, anosmia, ageusia) but also in the medium and long term (depression, anxiety disorders, schizophrenia, post-traumatic stress disorder, Guillain-Barre syndrome, Parkinson's disease or neurodegenerative conditions). The pathophysiological mechanisms, in particular immune mechanisms at the origin of the central nervous system damage, will be discussed. A strict longitudinal monitoring of these neuropsychiatric complications across all ages of the population is therefore necessary from now.