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DNA Microarrays

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

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Related Experiment Video

Updated: Nov 29, 2025

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics

Published on: October 5, 2016

From ArrayExpress to BioStudies.

Ugis Sarkans¹, Anja Füllgrabe¹, Ahmed Ali¹

¹European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK.

Nucleic Acids Research

|November 19, 2020

Summary

This summary is machine-generated.

ArrayExpress is migrating to the BioStudies database to harmonize functional genomics data archiving. Users will experience a seamless transition for data submission and access, with future data archived centrally in BioStudies.

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Last Updated: Nov 29, 2025

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Area of Science:

Genomics
Bioinformatics
Data Archiving

Background:

ArrayExpress, established in 2002, archived publication-related microarray and sequencing data.
Increasingly, biological experiments utilize multiple technologies for diverse data modalities.
The BioStudies database was developed to manage such multimodal experimental data.

Purpose of the Study:

To harmonize the functional genomics data archival infrastructure at EMBL-EBI.
To migrate the ArrayExpress archive to the BioStudies database.
To inform users about upcoming changes in data submission, querying, and programmatic access.

Main Methods:

Migration of ArrayExpress data and functionality to the BioStudies database.
Continued use of the Annotare tool for data submission.
Harmonization of metadata and data linking across EMBL-EBI resources.

Main Results:

ArrayExpress is being integrated into BioStudies, establishing a unified archive for functional genomics data.
Future functional genomics data will be exclusively archived in BioStudies.
The migration aims for a seamless user experience regarding data submission and retrieval.

Conclusions:

The migration of ArrayExpress to BioStudies represents a significant step in harmonizing functional genomics data archiving.
Users will benefit from a centralized data repository, although programmatic access methods will evolve.
This consolidation ensures efficient and unified access to diverse functional genomics datasets for the research community.