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Neurogenic rosacea in Korea
Hye One Kim1, Seok Young Kang1, Ko Eun Kim2
1Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
The Journal of Dermatology
|November 19, 2020
Summary
Neurogenic rosacea patients experience severe burning and stinging, often unresponsive to standard treatments. Anticonvulsants and antidepressants effectively treated most patients, suggesting a distinct classification and approach for this rosacea subtype.
Area of Science:
- Dermatology
- Neurology
Background:
- Rosacea, particularly subtypes with severe neurological symptoms like burning and stinging, presents challenges for conventional treatment.
- Korean patients with rosacea and prominent neurological symptoms require further investigation into their unique clinical characteristics.
Purpose of the Study:
- To investigate the clinical characteristics of Korean rosacea patients exhibiting significant neurological symptoms.
- To compare these patients with a control group of erythematotelangiectatic rosacea (ETR) patients.
Main Methods:
- A comparative study involving 17 patients with neurogenic rosacea and 17 neurological symptoms, and 106 patients with ETR.
- Data collected included demographic features, medical history, clinical manifestations, and treatment outcomes.
Main Results:
- All 17 neurogenic rosacea patients presented with severe persistent erythema and burning/stinging on the cheeks; 94.1% were female.
- Major aggravating factors included heat stimuli (58.8%) and stress (52.9%).
- A significant majority (82.3%) of neurogenic rosacea patients showed improvement with anticonvulsants and antidepressants.
Conclusions:
- Rosacea patients with severe neurological symptoms exhibit distinct clinical features.
- These patients may warrant separate classification due to their unique presentation.
- A tailored therapeutic strategy, potentially involving anticonvulsants and antidepressants, is indicated for neurogenic rosacea.
