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Updated: Nov 29, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Dynamic changes in computed tomography manifestations of 105 patients with novel coronavirus pneumonia in Wuhan,
Yueying Pan1, Liming Xia1, Yujin Wang1
1Radiology Department, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Objective:
To observe the evolution of chest high-resolution computed tomography (HRCT) manifestations in 105 patients with coronavirus disease 2019 (COVID-19).
Methods:
One hundred five patients with confirmed COVID-19 were enrolled from 11 January to 9 February 2020. Sequential chest HRCT examinations were performed. Five stages were identified from the onset of initial symptoms: 0-3, 4-7, 8-14, 15-21, and >21 days (Stages A-E, respectively). A semi-quantitative CT scoring system was used to estimate the sum of lung abnormalities in each stage.
Results:
In total, 393 CT scans were collected. The patients underwent 3.8 ± 1.5 CT examinations. Multiple lobes were involved in most cases. The proportion of consolidation and the total CT score gradually increased from Stage A to C and gradually decreased from Stage C to E. The total CT score of lung involvement was significantly higher in Stage C than in Stages B and D. The CT score of the lower lobe was significantly higher than the corresponding upper and middle lobes in Stages A to D.
Conclusions:
Most patients with COVID-19 had a disease course of >14 days, and the lung lesions in most patients improved after 14 days since initial symptom onset.
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