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Ideational Fluency in Patients with Rheumatoid Arthritis
Janis Mednieks1, Vladimrs Naumovs2, Jurgis Skilters1
1Department of Neurology and Neurosurgery, Riga Stradins University, Riga, Latvia.
Current Rheumatology Reviews
|November 20, 2020
Summary
Rheumatoid arthritis (RA) may impact cognitive function, specifically ideational fluency. This study found preliminary evidence of differences in cognitive performance between RA patients and controls, suggesting further research is needed.
Area of Science:
- Neuroscience
- Rheumatology
- Cognitive Psychology
Background:
- Systemic inflammatory conditions like rheumatoid arthritis (RA) are linked to neuropsychiatric symptoms.
- While cognitive decline and psychiatric issues are reported in RA patients, specific affected cognitive domains remain unclear.
Purpose of the Study:
- To assess ideational fluency in rheumatoid arthritis (RA) patients using the Thing Categories Test (TCT).
- To compare cognitive performance and screening scores for depression and anxiety between RA patients and a general population control group.
Main Methods:
- Utilized the Patient Health Questionnaire 9 (PHQ-9), Generalized Anxiety Disorder 7 (GAD-7), Montreal Cognitive Assessment (MoCA), and Thing Categories Test (TCT).
- Evaluated 20 patients with RA and 20 healthy controls.
Main Results:
- A statistically significant difference was observed in TCT performance for the category "blue" between RA patients and controls (p<0.025).
- RA patients showed slightly higher average scores for anxiety (GAD-7) and depression (PHQ-9) compared to controls.
- Montreal Cognitive Assessment (MoCA) scores were comparable between groups.
Conclusions:
- Preliminary findings suggest rheumatoid arthritis (RA) may affect the cognitive domain of ideational fluency.
- Larger studies are required to confirm these initial observations and provide more definitive conclusions on cognitive impacts in RA.
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