Ofloxacin adsorptive interaction with rice husk ash: Parametric and exhausted adsorbent disposability study

The present study investigates the adsorptive interaction of rice husk ash (RHA) with Ofloxacin (OFL) antibiotic. The OFL loaded RHA was studied for its disposability by solidification to find its possible use as a building material. Further, toxicity analysis of leachate from the solidified RHA was also studied for probable leaching of OFL. The effects of adsorption parameters such as initial pH, the dosage of RHA (m), initial OFL concentration (C₀), and contact time (t) on the responses % OFL removal (X₁) and adsorption capacity (mg/g) (X₂) were evaluated using the central composite design (CCD) based on response surface method (RSM). Kinetic and thermodynamic studies were performed at optimized parameters, and adsorption equilibrium data were illustrated by using Langmuir, Redlich-Peterson (R-P), and Tempkin isotherm models. Optimum condition was found as m = 7.94 g/L, t = 430 min and pH = 6, and at this actual responses X₁ and X₂ were evaluated as 79.71% and 6.28 mg/g, respectively. Pseudo-first-order kinetic fitted best for the adsorption kinetic data. Toxicity analysis of leachate from solidified RHA indicated that most of the OFL was encapsulated inside the cement and the OFL present in leachate is not sufficient to eradicate the growth of E.coli and Bacillus subtilis.