Related Experiment Video
Updated: Nov 29, 2025

Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
Bariatric Surgery Lowers the Risk of Major Cardiovascular Events
Andrew M Brown1, Jie Yang1, Xiaoyue Zhang2
1Department of Surgery, Stony Brook University Hospital, Stony Brook, New York.
Insights
Bariatric surgery significantly reduces the risk of heart attack and stroke. Gastric bypass surgery showed a lower risk of cardiovascular events compared to sleeve gastrectomy.
Area of Science:
- Cardiovascular Science
- Surgical Outcomes
- Obesity Medicine
Background:
- Bariatric surgery improves obesity-related comorbidities.
- Limited large-scale studies compare cardiovascular outcomes across different bariatric procedures.
Purpose of the Study:
- To evaluate the impact of bariatric surgery on myocardial infarction (MI), stroke, and composite cardiovascular events.
- To compare cardiovascular outcomes among different bariatric surgery types.
Main Methods:
- Retrospective, observational, matched-cohort study (2006-2012).
- Adult patients with obesity in New York state.
- Stratification by bariatric surgery utilization and procedure type (sleeve gastrectomy vs. gastric bypass).
Main Results:
- Bariatric surgery significantly reduced composite cardiovascular events (HR 0.48), MI (HR 0.39), and stroke (HR 0.55).
- Gastric bypass patients had a lower risk of MI, stroke, and overall cardiovascular events compared to sleeve gastrectomy patients.
Conclusions:
- Bariatric surgery is linked to a reduced risk of major cardiovascular events.
- Gastric bypass may offer superior cardiovascular protection compared to sleeve gastrectomy.
Objective:
This study examines the impact of bariatric surgery on the risk of myocardial infarction, stroke, and a composite of cardiovascular outcomes in a large population cohort. Additionally, the impact of different bariatric surgery procedures on cardiovascular outcomes is assessed and compared.
Summary Background Data:
Bariatric surgery has been shown to improve comorbid conditions that are associated with cardiovascular disease and death. Few large studies have examined the impact of bariatric surgery on cardiovascular outcomes, and specifically compared the different bariatric procedures.
Methods:
A retrospective, observational, matched-cohort study was conducted in adult patients with obesity in New York state from 2006 to 2012. Patients were stratified into 2 groups, based on utilization of bariatric surgery. Patients were further subgrouped based on the types of primary bariatric surgery. The primary endpoint was the development of specific cardiovascular events - myocardial infarction (MI), and stroke; as well as a composite of both events.
Results:
A total of 328,807 patients, including 60,445 who had undergone bariatric surgery, and 268,362 matched nonsurgical controls were the study cohort for comparing surgical and nonsurgical patients. The risk of composite cardiovascular events decreased in the surgical group [hazards ratio (HR) = 0.48, 95% confidence intervals (CI): 0.45-0.51], as did the risk of MI (HR = 0.39, 95% CI: 0.35-0.42), and stroke (HR = 0.55, 95% CI: 0.51-0.59). Among the surgical cohort, sleeve gastrectomy patients had a higher risk of developing MI, stroke, and any type of cardiovascular event than gastric bypass patients.
Conclusions:
Bariatric surgery is associated with decreased risk of significant cardiovascular events compared to nonsurgical controls. In this exploratory analysis, gastric bypass was associated with a lower risk of all cardiovascular events than sleeve gastrectomy.
Related Concept Videos
Atherosclerosis III: Management
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Coronary Artery Disease IV: Preventive Measures
Peripheral Artery Disease V: Postoperative Nursing Management

