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Updated: Nov 29, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
The Long-Term Effect of Medically Enhancing Melanin Intrinsic Bioenergetics Capacity in Prematurity
Arturo S Herrera1, Paola E Solís Arias1, María Del C A Esparza1
11Human Photosynthesis Study Centre, Aguascalientes, Mexico; 2Universidad Autónoma de Aguascalientes, Aguascalientes, Ags., Mexico; 3Asociación para Evitar la Ceguera en México, I.A.P., Mexico City, Mexico; 4I. M. Seche-nov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow101000, Russian Federation; 6Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow117418, Russian Federation; 7Department of Biological Sciences, Salem University, Salem, WV, USA; 8Institute of Physiologically Active Compounds of the Russian Academy of Sciences, Chernogolovka, Russia; 9GALLY International Research Institute, San Antonio, TX- 78229, USA.
Background:
The ability of the human body to produce metabolic energy from light modifies fundamental concepts of biochemistry.
Objective:
This review discusses the relationships between the long-accepted concept is that glucose has a unique dual role as an energy source and as the main source of carbon chains that are precursors of all organic matter. The capability of melanin to produce energy challenges this premise.
Methods:
The prevalent biochemical concept, therefore, needs to be adjusted to incorporate a newly discovered state of Nature based on melanin's ability to dissociate water to produce energy and to re-form water from molecular hydrogen and oxygen.
Results And Discussion:
Our findings regarding the potential implication of QIAPI-1 as a melanin precursor that has bioenergetics capabilities.
Conclusion:
Specifically, we reported its promising application as a means for treating retinopathy of prematurity (ROP). The instant report focuses on the long-term treatment medical effects of melanin in treating ROP.
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