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Updated: Nov 29, 2025

A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood
Published on: January 9, 2018
What the acute physician needs to know about Anti-NMDA receptor encephalitis: two case presentations
S L Gall1, S M Healy2, B D Michael2
1Royal Liverpool University Hospital, Liverpool, United Kingdom.
Abstract:
These case reports look at two patients with anti-N-methyl-D-aspartate receptor (NMDAr) encephalitis presenting to the same acute medical unit within a month of each other. The following covers the characteristic signs, symptoms and timeline associated with this condition and discusses whether we should be sending CSF for anti-NMDAr antibody testing more readily.
Insights
This case report highlights two patients with anti-N-methyl-D-aspartate receptor (NMDAr) encephalitis. It reviews the condition's symptoms and timeline, questioning the need for broader cerebrospinal fluid (CSF) testing.
Area of Science:
- Neurology
- Immunology
Background:
- Anti-N-methyl-D-aspartate receptor (NMDAr) encephalitis is a severe autoimmune neurological disorder.
- Prompt diagnosis and treatment are crucial for patient outcomes.
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