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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

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User-centric genomics infrastructure: trends and technologies.

Ritesh Krishna^1,1, Vadim Elisseev^1,1

¹IBM Research Europe, The Hartree Centre STFC Laboratory, Warrington WA4 4AD, UK.

|November 20, 2020

Summary

This summary is machine-generated.

Genomics informatics infrastructure must adapt to increasing data and computational demands. A user-centric approach is crucial for designing successful genomics infrastructure that supports bioinformaticians and data scientists.

Keywords:

big data bioinformatics bioinformatique calcul haute performance cloud données massives genomics génomique high performance computing infrastructure nuage

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Area of Science:

Genomics
Bioinformatics
Computational Biology
Data Science

Background:

Genomics is a data- and compute-intensive field.
Success relies on robust informatics infrastructure to handle data growth and computational needs.
Infrastructure design must consider user adoption and evolving requirements.

Purpose of the Study:

To examine genomics informatics infrastructure from a user-centric perspective.
To understand how data growth, big data, and cloud technologies impact computational activities.
To inform the design of future genomics infrastructures based on user needs.

Main Methods:

User-centric analysis of genomics computational activities.
Consideration of traditional and emerging computational tasks.
Evaluation of the influence of big data and cloud technologies.

Main Results:

Traditional genomics computational activities are expanding.
New user requirements are emerging due to data growth and new technologies.
User perspectives are critical for successful infrastructure design.

Conclusions:

Future genomics infrastructure design must be user-centric.
Adaptability to big data and cloud computing is essential.
Informatics infrastructure must evolve to meet the demands of modern genomics research.