Clinical characteristics of coronavirus disease 2019 (COVID-19) patients in Kuwait

Abdullah Alshukry1, Hamad Ali2,3, Yaseen Ali1

  • 1Department of Otolaryngology & Head and Neck Surgery, Jaber Al-Ahmad Hospital, Ministry of Health, South Surra, Kuwait.

Plos One
|November 20, 2020
PubMed

Insights

This study of 417 hospitalized coronavirus disease 2019 (COVID-19) patients in Kuwait found that 39.3% were asymptomatic. Of those admitted to the intensive care unit (ICU), 95.1% developed acute respiratory distress syndrome, with an overall mortality rate of 14.4%.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Critical Care Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) is a global pandemic.
  • Understanding the clinical characteristics and outcomes of hospitalized patients is crucial.

Purpose of the Study:

  • To describe the clinical features, complications, and outcomes of COVID-19 patients admitted to a hospital in Kuwait.
  • To identify risk factors for intensive care unit (ICU) admission and mortality.

Main Methods:

  • Retrospective single-center study of 417 consecutive COVID-19 patients.
  • Data collected on demographics, symptoms, comorbidities, ICU admission, complications, and mortality.
  • Chest high-resolution computed tomography (HRCT) and laboratory markers analyzed for ICU cases.

Main Results:

  • 39.3% of patients were asymptomatic, 41% had mild/moderate symptoms, and 19.7% required ICU admission.
  • Common symptoms included fever and dry cough; shortness of breath was prevalent in ICU admissions (75.6%).
  • ICU admissions were associated with sepsis (68.3%), acute respiratory distress syndrome (ARDS) (95.1%), heart failure (63.4%), and higher rates of diabetes and hypertension.
  • Mortality rate was 14.4%, with a mean age of death of 54.20 years, predominantly in males (90%).
  • Chest HRCT in ICU cases showed multifocal ground-glass opacities and consolidation.
  • Abnormal laboratory markers related to infection, inflammation, coagulation, cardiac, and kidney function were observed in ICU patients.

Conclusions:

  • A significant proportion of hospitalized COVID-19 patients in Kuwait were asymptomatic or had mild symptoms.
  • ARDS, sepsis, and heart failure were major complications leading to ICU admission.
  • Comorbidities like diabetes and hypertension were more common in severe cases requiring ICU care.
  • The study highlights the severity of COVID-19, with a notable mortality rate and specific radiological and laboratory findings in critically ill patients.

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