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Updated: Nov 29, 2025

Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets
Published on: September 13, 2022
Assessment of a downsized potassium adsorption filter designed to transfuse neonates
Kei Ogasawara1, Hitoshi Ohto2, Nozomi Takano2
1Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan.
Background:
During storage, the potassium level of red blood cell (RBC) components increases, especially after irradiation. Neonates are prone to hyperkalemia, for example, non-oliguric hyperkalemia, so using potassium adsorption filters during transfusion may be helpful. To overcome dilution of RBC components caused by saline priming of existing potassium adsorption filters, a downsized potassium adsorption filter for neonates (PAF-n, Kawasumi Laboratories Inc., Tokyo, Japan) was developed.
Study Design And Methods:
To assess the performance of PAF-n, its adsorption efficiency and RBC recovery rate were evaluated by testing pre-filtration and serial post-filtration (0-30 mL, 30-60 mL, 60-90 mL, and 90-120 mL) samples from 8 RBC components.
Results:
The average potassium adsorption rate of the PAF-n was 90.5% ± 0.78%, and never less than 89.0% in any of 8 RBC components. RBC recovery rates were 99.3% ± 1.12%.
Conclusion:
The PAF-n showed an effective potassium ability with negligible RBC dilution.
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