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Updated: Nov 29, 2025

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Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
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Predicting post stent fractional flow reserve virtually from quantitative flow ratio - Can we really get there from
Morton J Kern1, Arnold H Seto1
1Medicine, VA Long Beach Healthcare System, Long Beach, California.
Summary
This study found that post-percutaneous coronary intervention (PCI) quantitative flow ratio (QFR) better predicts fractional flow reserve (FFR) than residual QFR. Improved algorithms may enable post-PCI QFR for quality control, reducing angina and adverse outcomes.
Area of Science:
- Cardiovascular medicine
- Medical imaging
- Interventional cardiology
Background:
- Accurate assessment of coronary artery stenosis post-percutaneous coronary intervention (PCI) is crucial for optimizing outcomes.
- Fractional flow reserve (FFR) is the gold standard for assessing lesion significance, but it is invasive.
- Quantitative flow ratio (QFR) derived from angiography offers a non-invasive alternative.
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