Related Experiment Videos
Increase of insulin and decrease of glucagon levels in response to total and fractionated weaning in sows
M Eriksson1, S Einarsson, A Kunavongkrit
1Department of Pharmacology, Karolinska Institute, Stockholm, Sweden.
Acta Physiologica Scandinavica
|November 1, 1987
Summary
Weaning in sows significantly alters insulin and glucagon levels, impacting glucose regulation. These hormonal shifts may be linked to changes in mammary gland activity and insulin sensitivity post-weaning.
Area of Science:
- Reproductive Endocrinology
- Animal Physiology
Background:
- Lactation and weaning are critical physiological transitions in sows.
- Hormonal regulation of glucose metabolism is essential for maternal health.
Purpose of the Study:
- To investigate the effects of different weaning strategies on plasma insulin, glucagon, and glucose levels in sows.
- To explore potential mechanisms behind observed hormonal and metabolic changes.
Main Methods:
- Studied sows undergoing final weaning (all piglets removed) and fractionated weaning (partial removal).
- Measured plasma insulin, glucagon, and glucose levels at specific time points post-weaning.
Main Results:
- Insulin levels significantly increased after both final and fractionated weaning.
- Glucagon levels decreased in both weaning groups.
- Plasma glucose levels increased after fractionated weaning but remained unchanged after final weaning.
Conclusions:
- Weaning induces significant hormonal changes in sows, including elevated insulin and reduced glucagon.
- Plasma glucose alterations suggest differential metabolic responses to weaning strategies.
- Potential mechanisms involve changes in mammary gland function and insulin resistance.