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Updated: Nov 29, 2025

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
18F-FDG PET Imaging Predicts the Epileptogenic Zone Prospectively in Recurrent Cryptogenic Meningoencephalitis with
1Nuclear Medicine and Molecular Imaging, Sidra Medicine, Doha, Qatar mdjekidel@sidra.org.
Abstract:
18F-FDG PET scans have proven to be useful in the diagnosis and management of encephalitis patients. 18F-FDG PET scans are also the standard of care in the evaluation of epilepsy patients before surgery. Encephalitis patients who later develop epilepsy may have useful imaging findings at the time of diagnosis. We present a case of 18F-FDG PET imaging in a patient with recurrent cryptogenic meningoencephalitis. 18F-FDG PET imaging after resolution of the encephalitis revealed hypometabolism in previously hypermetabolic areas. Hence, the initial 18F-FDG PET scan prospectively predicted the epileptogenic zone and seizure-onset zone.
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