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From dermatological conditions to COVID-19: Reasoning for anticoagulation, suppression of inflammation, and
Paulo Ricardo Criado1, Hélio Amante Miot2, Thais Prota Hussein Pincelli3
1Department of Dermatology, Centro Universitário Saúde ABC, Santo André, São Paulo, Brazil.
Abstract:
COVID-19 generates a complex systemic inflammatory response that can lead to death due to wide macrophage activation, endothelial damage, and coagulation in critically ill patients. SARS-CoV-2-induced lung injury due to inflammatory mediated thrombosis could be similar to the livedoid vasculopathy in the skin, supporting a translational comparison of these clinical settings. In this article, we discuss anticoagulation, suppression of inflammatory response, and hyperbaric oxygen therapy in the context of severe COVID-19 and livedoid vasculopathy.
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