Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.6K
Diamagnetic Shielding of Nuclei: Local Diamagnetic Current01:14

Diamagnetic Shielding of Nuclei: Local Diamagnetic Current

1.1K
An applied magnetic field causes the electrons present in the molecule to circulate, setting up a local diamagnetic current within the molecule. The local diamagnetic current arising from circulating sigma-bonding electrons induces a magnetic field, Blocal that opposes the applied magnetic field, B0. The effective magnetic field experienced by these nuclei is given by the difference between the applied and local magnetic fields in a phenomenon called local diamagnetic shielding. Essentially,...
1.1K
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

1.1K
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
1.1K
Mass Spectrometers01:16

Mass Spectrometers

7.8K
This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
7.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Proton RBE for in vivo model systems: LET and dose dependencies for early and late biological endpoints.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2026
Same author

Prospective blinded clinical evaluation of a fully automated workflow for prostate radiotherapy.

Physics and imaging in radiation oncology·2026
Same author

Assessing the quality of deformable image registration in magnetic resonance image guided carbon ion liver radiotherapy with an anthropomorphic phantom.

Physics and imaging in radiation oncology·2026
Same author

Nanomotor-Assisted Intravesical Chemotherapy for Bladder Tumor Reduction and Suppression of Early Tumor Regrowth.

Nano letters·2026
Same author

Towards a shuttle-based workflow for daily online magnetic resonance imaging-guided particle therapy: Anatomical robustness and organ variability in the female pelvis.

Technical innovations & patient support in radiation oncology·2026
Same author

Multicenter End-to-End Evaluation of Single-Isocenter Multitarget Stereotactic Radiosurgery Approaches: Accuracy and Plan Quality.

International journal of radiation oncology, biology, physics·2026

Related Experiment Video

Updated: Nov 29, 2025

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
07:31

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

Published on: May 9, 2014

12.1K

Dosimetry in magnetic fields with dedicated MR-compatible ionization chambers.

Bhargesh K Shukla1, Claudia Katharina Spindeldreier2, Oliver Schrenk3

  • 1Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiooncology (HIRO), Heidelberg, Germany.

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
|November 21, 2020
PubMed
Summary

This study validates MR-compatible ionization chambers for magnetic fields in radiotherapy. Results show minimal response changes, ensuring accurate dosimetry during MR-guided treatments.

Keywords:
Dosimetry in magnetic fieldsEGSnrcMR-compatible ionization chambersMR-guided radiotherapyMR-linacMonte-Carlo simulationPolarity effectRecombination effect

More Related Videos

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

5.3K
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.5K

Related Experiment Videos

Last Updated: Nov 29, 2025

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
07:31

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

Published on: May 9, 2014

12.1K
Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

5.3K
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.5K

Area of Science:

  • Medical Physics
  • Radiotherapy Dosimetry
  • Magnetic Resonance Imaging

Background:

  • MR-integrated radiotherapy necessitates dosimetry detectors functional within magnetic fields.
  • Existing ionization chambers may not perform accurately under these conditions.

Purpose of the Study:

  • To assess the feasibility and performance of MR-compatible ionization chambers in magnetic fields.
  • To simulate and measure the response of specific ionization chambers during MR-integrated radiotherapy.

Main Methods:

  • Utilized EGSnrc Monte Carlo simulations to model MR-compatible ionization chambers (Exradin A19MR, A1SLMR, A26MR, A28MR).
  • Simulated magnetic field effects in transverse and parallel orientations.
  • Validated simulations with experimental measurements up to 1.1 T in transverse orientation.

Main Results:

  • Simulations and measurements showed good agreement, except for the A26MR in transverse orientation.
  • Maximum response increase observed was 8.6% in the transverse orientation.
  • No significant response change occurred when the magnetic field was parallel to the chamber and beam axis. Polarity and recombination effects were unaffected by magnetic fields.

Conclusions:

  • MR-compatible ionization chambers are feasible for MR-integrated radiotherapy.
  • Chamber response is largely stable in magnetic fields, with orientation-dependent variations.
  • Further investigation into rotational symmetry is needed for non-symmetric chambers.