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[Follow-up and evaluation of non-neurogenic OAB treatments]
1Service d'urologie, hôpital Pitié-Salpêtrière, AP-HP Sorbonne université, Paris, France.
Introduction:
The purpose of monitoring a patient treated for overactive bladder (OAB) is to ensure the effectiveness of the treatment and to detect any side effects.
Objective:
To synthesize current knowledge on the follow-up and the evaluation of non-neurogenic OAB treatments.
Method:
A systematic literature review based on Pubmed, Embase, Google Scholar was conducted in June 2020.
Results:
The definition of success of OAB treatments is not consensual. Definitions of success in clinical trials usually use bladder diary data. However, they cannot always be transposed into clinical practice because they do not measure the overall effectiveness of a treatment, reported by the patient, or the satisfaction with the treatment. It is then necessary to have symptom questionnaires with an assessment of quality of life. Indeed, the concept of therapeutic success is different depending on the view of the physician or the patient. It is therefore important to carefully assess with the patient, and before initiating any treatment, the objectives and expected results of the treatment. The definition of "refractory" OAB is heterogeneous but important to select candidates for second-line treatments. Monitoring a patient with OAB is essential to adapt the treatment to efficacy and tolerance, but also to detect any change in symptoms that may reveal another urological disease.
Conclusion:
The success or failure of OAB treatments depends on the interaction of many factors, including objective criteria measured by the clinician, and subjective criteria of perception of the treatment effectiveness by the patient.
Insights
Monitoring overactive bladder (OAB) treatment requires assessing both objective clinical data and patient-reported outcomes for effective management. Patient satisfaction and quality of life are crucial for defining successful OAB treatment.
Area of Science:
- Urology
- Pharmacology
- Patient-centered care
Background:
- Effective monitoring of overactive bladder (OAB) treatments is vital for assessing efficacy and detecting adverse events.
- Current OAB management focuses on ensuring treatment effectiveness and identifying potential side effects.
Purpose of the Study:
- To synthesize current knowledge regarding the follow-up and evaluation of non-neurogenic overactive bladder (OAB) treatments.
- To provide a comprehensive overview of best practices in OAB treatment monitoring.
Main Methods:
- A systematic literature review was performed using major scientific databases: Pubmed, Embase, and Google Scholar.
- The literature search was conducted in June 2020 to capture the latest research.
Main Results:
- The definition of successful overactive bladder (OAB) treatment is not universally agreed upon, with clinical trials often relying on bladder diary data.
- Patient-reported outcomes, including overall effectiveness and treatment satisfaction, are essential and may not be fully captured by diary data alone.
- Assessing quality of life through symptom questionnaires is necessary, as therapeutic success perception differs between patients and physicians. Setting clear treatment objectives with patients is crucial.
Conclusions:
- The success of overactive bladder (OAB) treatments is multifactorial, influenced by both objective clinical measures and subjective patient perceptions.
- Continuous patient monitoring is key to adapting treatments based on efficacy and tolerance, and to identify any new or evolving urological conditions.
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