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The association between body mass index class and coronavirus disease 2019 outcomes
Abdallah Al-Salameh1,2, Jean-Philippe Lanoix3, Youssef Bennis4
1Department of Endocrinology, Diabetes Mellitus and Nutrition, Amiens University Hospital, Amiens, France. al-salameh.abdallah@chu-amiens.fr.
Insights
Overweight and obesity increase the risk of intensive care unit (ICU) admission for patients with coronavirus disease 2019 (COVID-19). Obesity is also linked to a higher risk of death from COVID-19.
Area of Science:
- Medical Research
- Epidemiology
- Public Health
Background:
- Growing evidence links obesity to increased severity of coronavirus disease 2019 (COVID-19).
- Understanding the impact of body mass index (BMI) categories on COVID-19 outcomes is crucial for patient management.
Purpose of the Study:
- To investigate the association between different body mass index (BMI) categories and critical forms of COVID-19.
- To determine if overweight and obesity correlate with intensive care unit (ICU) admission or death in COVID-19 patients.
Main Methods:
- Retrospective analysis of adult patients hospitalized with confirmed COVID-19 at Amiens University Hospital.
- Logistic regression analysis to assess the association between BMI categories and a composite endpoint of ICU admission or death.
Main Results:
- Of 329 patients with available BMI data, 37.7% were obese and 27.4% were overweight.
- Both overweight and obesity were associated with increased odds of ICU admission (ORs 3.16 and 3.05, respectively).
- Obesity, but not overweight, was significantly associated with a higher risk of death after adjustment for other factors.
Conclusions:
- Overweight status, in addition to obesity, is linked to a higher likelihood of ICU admission for COVID-19 patients.
- Obesity is a significant risk factor for mortality in COVID-19 patients.
- BMI should be considered in assessing the prognosis of COVID-19 patients.
Background/Objectives:
A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study's primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19.
Subjects/Methods:
Data on consecutive adult patients hospitalized with laboratory-confirmed COVID-19 at Amiens University Hospital (Amiens, France) were extracted retrospectively. The association between BMI categories and the composite primary endpoint (admission to the intensive care unit or death) was probed in a logistic regression analysis.
Results:
In total, 433 patients were included, and BMI data were available for 329: 20 were underweight (6.1%), 95 have a normal weight (28.9%), 90 were overweight (27.4%), and 124 were obese (37.7%). The BMI category was associated with the primary endpoint in the fully adjusted model; the odds ratio (OR) [95% confidence interval (CI)] for overweight and obesity were respectively 1.58 [0.77-3.24] and 2.58 [1.28-5.31]. The ORs [95% CI] for ICU admission were similar for overweight (3.16 [1.29-8.06]) and obesity (3.05 [1.25-7.82]) in the fully adjusted model. The unadjusted ORs for death were similar in all BMI categories while obesity only was associated with higher risk after adjustment.
Conclusions:
Our results suggest that overweight (and not only obesity) is associated with ICU admission, but overweight is not associated with death.
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