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Updated: Nov 29, 2025
Author Spotlight: Eco-Friendly Extraction of Bioactive Compounds Using Polyol-Based Microwave-Assisted Techniques
Published on: August 23, 2024
Microwave irradiation is a suitable method for caulerpin extraction from the green algae Caulerpa racemosa
Sarah J Cantarino1,2, Ricardo Coutinho1,2, Angélica R Soares1,3
1Programa de Pós-graduação em Biotecnologia Marinha, Instituto de Estudos do Mar Almirante Paulo Moreira/Universidade Federal Fluminense, Arraial do Cabo, Brazil.
Abstract:
Caulerpin is a bisindolic alkaloid that has been obtained from many species of the genus Caulerpa. The main objective of this paper is to evaluate four extraction methods of caulerpin in the C. racemosa: maceration (DMA), Soxhlet extraction (SOX), ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE). The methods were compared through caulerpin content quantified by Ultraviolet-visible (UV-vis) spectrophotometry. The highest extract yield was obtained by SOX but the highest contain of caulerpin was presented in the MAE extract. The caulerpin content was significant different within the extacts by MAE and UAE, it yielded by MAE more than three times as much as UAE. The most efficient caulerpin extraction method had the parameters solvent, temperature and time optimised. Thus, the best conditions were achieved with MAE in ethanol during 7 min at 90 °C. Therefore, this work suggests an improved routine analysis of caulerpin by the green chemistry concept.
