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Inadvertent Methylergonovine administration to a newborn.

Kayla Wilson¹, Rafael Santiago¹, Mark Preziosi²

¹Department of Emergency Medicine, Lakeland Regional Health, Lakeland, FL, United States of America.

The American Journal of Emergency Medicine

|November 23, 2020

Summary

Inadvertent methylergonovine administration to newborns can cause severe respiratory distress and cyanosis. Emergency medicine providers must maintain vigilance for this rare, life-threatening event in neonates.

Keywords:

Intramuscular Methergine Newborn Toxicity

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Area of Science:

Neonatal Medicine
Emergency Medicine
Pharmacology

Background:

Methylergonovine is used postpartum to prevent uterine hemorrhage.
Accidental administration to neonates is a rare but documented adverse event.
No previous case reports exist in emergency medicine literature.

Observation:

A 5-hour-old neonate presented to the emergency department with apnea and cyanosis.
The infant had inadvertently received methylergonovine.
The neonate required intubation and mechanical ventilation.

Findings:

Inadvertent methylergonovine exposure in neonates can lead to severe respiratory compromise.
Neonatal intensive care unit (NICU) admission and prolonged support may be necessary.
This case highlights a potential medication error in community settings.

Implications:

Emergency medicine providers should be aware of the risks of methylergonovine in neonates.
Heightened vigilance is crucial when managing newborns in the early hours of life.
This case underscores the importance of medication safety protocols to prevent neonatal harm.