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The effect of captopril on cutaneous blood flow in patients with primary Raynaud's phenomenon
M H Rustin1, N E Almond, J A Beacham
1Department of Dermatology, Middlesex Hospital, London, U.K.
The British Journal of Dermatology
|December 1, 1987
Abstract:
Fifteen patients with primary Raynaud's phenomenon received captopril 25 mg or placebo, three times daily for 6 weeks, in a randomized double-blind cross-over study. Compared with placebo, captopril produced a significant improvement in cutaneous blood flow but did not alter the frequency or severity of attacks of Raynaud's phenomenon.