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Depression and Quality of Life after Cerebral Venous Sinus Thrombosis

Aralikatte O Saroja1, Ninad N Thorat1, Karkal R Naik1

  • 1Department of Neurology, Jawaharlal Nehru Medical College, Nehru Nagar, Belagavi, Karnataka, India.

Annals of Indian Academy of Neurology
|November 23, 2020
PubMed

Insights

Cerebral venous sinus thrombosis (CVST) can lead to significant depression and psychosocial impairment, even with good physical recovery. This study highlights the need to assess mental health in CVST survivors.

Area of Science:

  • Neurology
  • Psychiatry
  • Public Health

Background:

  • Cerebral venous sinus thrombosis (CVST) is a significant cause of stroke in young adults, often with a favorable prognosis.
  • However, long-term consequences can include motor and cognitive deficits, depression, anxiety, fatigue, and reduced quality of life.

Purpose of the Study:

  • To evaluate the prevalence of depression and assess the quality of life in patients following Cerebral Venous Sinus Thrombosis (CVST).

Main Methods:

  • A cross-sectional observational study included 100 patients at least 1 year post-discharge from a CVST cohort.
  • Quality of life was measured using the Stroke-Adapted Sickness Impact Profile (SA-SIP 30).
  • Depression was assessed using the Hamilton Depression scale (HAM-D).

Main Results:

  • 98% of patients had good functional outcomes (modified Rankin score).
  • Despite good physical function, 7 patients experienced psychosocial impairment.
  • 30 patients (30%) were diagnosed with depression, which correlated with higher modified Rankin scores at discharge.

Conclusions:

  • This study is the first in India to report depression rates and quality of life using SA-SIP in CVST patients.
  • The prevalence of depression in CVST survivors is comparable to that observed in arterial stroke patients.
Abstract

Keywords:
Cerebral venous sinus thrombosisHamilton Depression scalepost-stroke depressionquality of life

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