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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
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Rapidly progressive organizing pneumonia associated with COVID-19
Hiroshi Horii1, Keisuke Kamada1, Sho Nakakubo1
1Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
Respiratory Medicine Case Reports
|November 23, 2020
Summary
This case study highlights secondary organizing pneumonia (SOP) in a COVID-19 patient. Corticosteroid treatment improved respiratory failure, suggesting its benefit for COVID-19-associated lung complications.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- Coronavirus disease 2019 (COVID-19) can lead to various pulmonary complications.
- Secondary organizing pneumonia (SOP) is a potential, though less common, manifestation requiring clinical awareness.
Observation:
- A 70-year-old female COVID-19 patient developed rapid respiratory failure despite initial symptom improvement.
- Computed tomography revealed bilateral lung consolidation, indicating severe lung injury.
- Blood biomarkers Krebs von den Lungen-6 (KL-6) and surfactant protein D (SP-D) exhibited distinct patterns during the disease course.
Findings:
- Corticosteroid therapy led to significant improvement in dyspnea, oxygenation, and radiological findings.
- Serial monitoring of KL-6 and SP-D may aid in diagnosing and managing COVID-19-associated organizing pneumonia (OP).
Implications:
- Clinicians must consider SOP as a complication of COVID-19.
- Early recognition and corticosteroid treatment can be beneficial for patients with COVID-19-associated SOP.
- Further research into the role of biomarkers like KL-6 and SP-D in COVID-19 lung disease is warranted.
Keywords:
COVID-19COVID-19, coronavirus disease 2019CorticosteroidsKL-6, Krebs von den Lungen 6Krebs von den lungen 6 (KL-6)OP, organizing pneumoniaOrganizing pneumoniaSARS-CoV-2SARS-CoV-2, severe acute respiratory syndrome coronavirus 2SOP, secondary organizing pneumoniaSP, surfactant proteinSurfactant protein (SP-D)
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