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Recurrent ventricular septal defect following closure CorMatrix: A case report.
Haytham Mously1, Joseph Kim1, Heather L Wheat2
1Department of Cardiovascular Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Journal of Cardiac Surgery
|November 23, 2020
Summary
A patient experienced ventricular septal rupture repair with a CorMatrix patch, which later reabsorbed. This case highlights the need for more research on long-term outcomes of this regenerative medicine approach for myocardial infarction complications.
Area of Science:
- Cardiovascular Surgery
- Regenerative Medicine
- Biomaterials Science
Background:
- Ventricular septal rupture (VSR) is a rare but serious complication of acute myocardial infarction (MI).
- Surgical patch closure is the standard treatment for VSR to restore hemodynamic stability.
- Extracellular matrix (ECM) biomaterials, like small intestinal submucosa (SIS), are increasingly used as scaffolds for tissue repair.
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