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Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States

Connie A Haley, Patricia Macias, Supriya Jasuja

Emerging Infectious Diseases

|November 23, 2020

Abstract:

The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose.

Keywords:

BPaL Nix-TB United States antimicrobial resistance bacteria bedaquiline drug monitoring linezolid pretomanid tuberculosis and other mycobacteria

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