Implications of the neglect of stereochemistry in pharmacokinetics and clinical pharmacology
Related Experiment Videos
1Institute of Pharmacology and Toxicology, University of Nijmegen, The Netherlands.
Drug Intelligence & Clinical Pharmacy
|October 1, 1987
Abstract:
An outline is given of the implications of stereoselectivity in biological action and the use of racemic fixed-ratio combinations in pharmacology and pharmacotherapeutics. Pitfalls of the neglect of stereochemistry, such as generation of senseless pharmacokinetic data, are exemplified and emphasized.