Intestinal emphysema (Pneumatosis cystoides intestinalis) in a gnotobiotic pig

A gnotobiotic pig monocontaminated with an enteropathogenic Escherichia coli was subsequently hyperimmunized to produce a monotypic antiserum. At necropsy, multiple, air filled cysts were found in the wall of the large intestine. The etiology of this condition is still conjectural. However, select strains of E. coli may cause or contribute to intestinal emphysema in swine.