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Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis

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Trochlear Morphology Development: Study of Normal Pediatric Knee MRIs.

Myra Trivellas¹, Benjamin Kelley, Nicole West

¹UCLA/DGSOM, UCLA Department of Orthopedics, Orthopedic Institute for Children, Los Angeles, CA.

Journal of Pediatric Orthopedics

|November 24, 2020

Summary

This summary is machine-generated.

This study defines normal trochlear morphology development in pediatric patients. Articular cartilage and subchondral bone measurements show significant changes with age, indicating final trochlear shape is established around age 12.

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Area of Science:

Pediatric orthopedics
Radiology
Biomedical engineering

Background:

Trochlear dysplasia is a risk factor for patellar dislocations.
Normal trochlear development is not well understood.
This study aims to define trochlear morphology development in children.

Purpose of the Study:

To establish normative data for trochlear morphology development in pediatric patients.
To analyze the changes in articular cartilage (AC) and subchondral bone (SCB) trochlear morphology with age.
To identify predictors of final trochlear shape.

Main Methods:

Retrospective review of 246 knee MRIs from 230 pediatric patients (ages 3-16).
Measurements of linear (LTH, MTH, CTH) and angular (SA, LTS, MTS) parameters at AC and SCB.
Analysis of age-related changes using linear regression, summarized by age quartiles.

Main Results:

Linear dimensions (LTH, MTH, CTH) increased with age at both AC and SCB.
Angular dimensions at SCB showed significant age-related changes (LTS, MTS increased; SA decreased).
AC measurements for LTS and SA remained constant, suggesting they predict final trochlear shape.

Conclusions:

Trochlear morphology, particularly SCB dimensions, develops significantly throughout childhood.
AC measurements of LTS and SA are stable and predict final trochlear shape.
Normal trochlear development is largely complete by age 12.