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Arrhythmias Associated with Inflammatory Cardiomyopathies
Roshan Karki1, Chaitra Janga1, Abhishek J Deshmukh1
1Division of Cardiovascular Disease, Mayo Clinic, 200 1st Street, Rochester, MN 55905 USA.
Insights
Arrhythmias are common in inflammatory cardiomyopathies. This review outlines current diagnostic and treatment strategies for managing these complex cardiac conditions, focusing on cardiac sarcoidosis.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiomyopathy Research
Background:
- Inflammatory cardiomyopathies are a growing cause of cardiac arrhythmias.
- Recent research offers new insights into arrhythmia development and management.
Purpose of the Study:
- To present a diagnostic and treatment approach for arrhythmias in inflammatory cardiomyopathies.
- To highlight challenges in managing these arrhythmias due to dynamic pathophysiology.
Main Methods:
- Review of recent studies on arrhythmia pathogenesis.
- Evaluation of diagnostic tools for inflammatory cardiomyopathies.
- Analysis of current treatment strategies.
Main Results:
- Inflammatory cardiomyopathies frequently cause ventricular and supraventricular arrhythmias.
- Common arrhythmias include atrioventricular block and tachyarrhythmias.
- Sudden cardiac death is a potential complication.
Conclusions:
- Management of arrhythmias in inflammatory cardiomyopathies is challenging.
- A structured approach to diagnosis and treatment is essential.
- Cardiac sarcoidosis serves as a key example in this review.
Purpose Of Review:
To provide an approach to the diagnosis and treatment of arrhythmias associated with inflammatory cardiomyopathies.
Recent Findings:
Inflammatory cardiomyopathies are increasingly recognized as the etiology of both ventricular and supraventricular arrhythmias. There have been recent studies providing novel insights into the pathogenesis of arrhythmias in inflammatory cardiomyopathies and exploring the role of various diagnostic tools and treatment strategies.
Summary:
Patients with inflammatory cardiomyopathies often present with one or more arrhythmias, including atrioventricular block, atrial and ventricular tachyarrhythmias, and occasionally sudden cardiac death. Given dynamic pathophysiology and heterogeneous presentation, the management of arrhythmias in these patients presents unique challenges. We review the current approach to the diagnosis and treatment of arrhythmias in this challenging cohort of patients with an emphasis on cardiac sarcoidosis.
Supplementary Information:
The online version of this article (10.1007/s11936-020-00871-5) contains supplementary material, which is available to authorized users.
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