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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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Comparison of stroke care parameters in acute ischemic stroke patients with and without concurrent Covid-19. A

Daniel Richter1, Christos Krogias1,2, Jens Eyding2,3

  • 1Department of Neurology, St. Josef-Hospital Bochum, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.

Neurological Research and Practice
|November 24, 2020
PubMed

Insights

Patients with acute ischemic stroke (AIS) and COVID-19 had similar rates of IV thrombolysis but lower mechanical thrombectomy rates and significantly higher in-hospital mortality compared to non-infected AIS patients.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic presents unique challenges for managing acute ischemic stroke (AIS).
  • Understanding the interplay between AIS and SARS-CoV-2 infection is crucial for optimizing patient care.
  • Comparing outcomes in AIS patients with and without COVID-19 can inform clinical and public health strategies.

Purpose of the Study:

  • To compare healthcare parameters, treatment characteristics, and in-hospital mortality between AIS patients with and without concurrent COVID-19.
  • To analyze nationwide data from Germany during the early phase of the pandemic.

Main Methods:

  • Utilized a nationwide administrative database of hospitalized AIS patients from January 16th to May 15th, 2020.
  • Included data from 1463 hospitals in Germany.
  • Compared case numbers, intravenous thrombolysis (IVT), mechanical thrombectomy (MT), intensive care unit (ICU) or stroke unit treatment, and in-hospital mortality.

Main Results:

  • Identified 213 AIS patients with concurrent COVID-19 among 30,864 COVID-19 patients.
  • AIS patients with COVID-19 had similar IVT rates (16.4% vs. 16.5%) but significantly lower MT rates (3.8% vs. 7.9%) compared to 68,700 AIS patients without COVID-19.
  • In-hospital mortality was significantly higher in AIS patients with COVID-19 (22.5%) versus those without (7.8%).

Conclusions:

  • Nationwide data reveal distinct differences in mortality and treatment between AIS patients with and without COVID-19.
  • AIS is a less common but frequently fatal comorbidity in COVID-19 patients.
  • These findings underscore the need for vigilant management of AIS during the ongoing pandemic.
Abstract

Keywords:
Covid-19StrokeThrombectomyThrombolysis

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