Related Experiment Video
Updated: Nov 29, 2025
02:21
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
1.1K
Progress on Management of Penile Cancer in 2020
Mohamed E Ahmed1, Mahmoud I Khalil2, Mohamed H Kamel2
1Department of Urology, Mayo Clinic, Rochester, MN, USA.
Current Treatment Options in Oncology
|November 24, 2020
Summary
Penile cancer management has advanced, favoring organ-preserving surgeries and minimally invasive techniques. New systemic therapies offer hope for advanced cases, improving patient quality of life.
Area of Science:
- Urologic Oncology
- Medical Oncology
Background:
- Penile cancer is rare, posing management challenges with significant patient impact.
- Squamous cell carcinoma is the predominant histologic subtype.
- Penile cancer contributes to approximately 1% of annual cancer deaths in the USA.
Purpose of the Study:
- To update clinicians on recent advances in penile cancer diagnosis and treatment.
- To summarize current guidelines and recommendations for penile cancer management.
Main Methods:
- Review of literature on diagnostic and therapeutic advancements.
- Analysis of trends towards organ-preserving procedures and minimally invasive surgery.
- Investigation of novel systemic therapies for advanced and metastatic penile cancer.
Main Results:
- Shift from radical surgery to penile-preserving techniques for many patients.
- Implementation of minimally invasive approaches for lymph node management.
- Promising outcomes reported for new systemic therapies in advanced disease.
Conclusions:
- Significant progress in penile cancer management improves patient quality of life.
- Current trends focus on less invasive treatments and novel systemic options.
- Updated clinical guidelines reflect these therapeutic advancements.
More Related Videos
Related Concept Videos
02:57Targeted Cancer Therapies
8.2K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
8.2K
02:56Treatment Resistant Cancers
3.5K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.5K
01:20Disorders of the Male Reproductive System
3.8K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
3.8K
01:21Cancer Survival Analysis
539
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
539
02:07Tumor Progression
7.0K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.0K
01:25Urinary Tract Calculi VI: Surgical Management
163
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
163