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External use of Mirabilite combined with Lactulose improves postoperative gastrointestinal mobility among older

Wenyan Pan1, Shining Cai1, Jos M Latour2

  • 1Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai, China.

Journal of Advanced Nursing
|November 24, 2020
PubMed
Abstract

Insights

Mirabilite combined with Lactulose improved postoperative gastrointestinal mobility in older patients. This combination therapy enhanced bowel function recovery and reduced hospital stays for surgical intensive care unit patients.

Area of Science:

  • Gastroenterology
  • Surgical Critical Care
  • Pharmacology

Background:

  • Postoperative gastrointestinal tract dysfunction (PGITD) is a common complication in older patients following abdominal surgery.
  • Effective interventions are needed to improve recovery and reduce patient suffering.

Purpose of the Study:

  • To evaluate the feasibility and efficacy of using Mirabilite combined with Lactulose for older patients experiencing PGITD.
  • To assess the impact of this combined therapy on gastrointestinal motility and patient outcomes.

Main Methods:

  • A retrospective observational cohort study comparing patients who received Mirabilite + Lactulose with those who received Lactulose alone.
  • Analysis of medical records from surgical intensive care unit patients aged over 60 years with PGITD between January 2017 and December 2018.

Main Results:

  • The Mirabilite + Lactulose group showed a significantly higher recovery rate of bowel sounds (62.16% vs. 37.63%) and a greater incidence of flatus or defecation (70.27% vs. 46.24%).
  • This combination therapy led to significant reductions in abdominal girth, inter-abdominal pressure, and pain scores compared to Lactulose alone.
  • Patients receiving Mirabilite + Lactulose experienced a shorter hospital stay (12.5 vs. 13.9 days).

Conclusions:

  • External application of Mirabilite combined with Lactulose is a feasible and effective intervention for improving postoperative gastrointestinal mobility in older intensive care patients.
  • This painless, safe, and easily implementable therapy offers a valuable option for alleviating suffering in postoperative patients with PGITD.
Keywords:
Mirabiliteintensive careintra-abdominal surgerynursingpostoperative gastrointestinal mobility

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