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Clinical Features of COVID-19 in Uzbekistan

KyungHee Kim¹, Jae Wook Choi^1,2,3, Juyoung Moon^1,2

¹Institute for Environmental Health, Korea University, Seoul, Korea.

Journal of Korean Medical Science

|November 24, 2020

Insights

COVID-19 patients in Uzbekistan were predominantly male, with fatigue and dry cough being the most common symptoms. Clinical characteristics varied by age and severity, informing future public health strategies.

Area of Science:

Epidemiology
Infectious Diseases
Public Health

Background:

Uzbekistan confirmed 2,039 COVID-19 cases by April 30, 2020.
COVID-19 symptoms range from asymptomatic to fatal.
This study analyzes symptomatic and clinical characteristics of hospitalized COVID-19 patients in Uzbekistan.

Purpose of the Study:

To analyze symptomatic and clinical characteristics of COVID-19 patients in Uzbekistan.
To provide data for developing effective public health policies.
To inform resource distribution based on patient demographics and disease severity.

Main Methods:

Data collected from medical records of 1,030 COVID-19 patients hospitalized across 19 hospitals in Uzbekistan.
Included demographics, symptoms, clinical outcomes, and treatment data.
Analysis focused on patients discharged after treatment between March 15 and April 30, 2020.

Main Results:

Males constituted 57.6% of cases; median age was 36.0 years.
Most frequent symptoms: fatigue (59.7%), dry cough (54.1%), pharyngalgia (31.6%).
Younger patients had fewer symptoms; older patients (50-84) required more oxygen support. ICU patients were more likely to have returned from abroad and included a higher percentage of asymptomatic cases.

Conclusions:

Clinical characteristics vary by age and severity, necessitating tailored medical delivery systems.
Data supports the need for age and severity-based resource allocation for future pandemic response.
Findings provide crucial primary data for Uzbekistan's COVID-19 policy development.

Read full analysis

Abstract

Background:

As of April 30, 2020, a total of 2,039 cases of the novel coronavirus disease 2019 (COVID-19) were confirmed in the Republic of Uzbekistan after the first detection on March 15. Reports on symptoms of COVID-19 are non-specific and known to vary from asymptomatic, mild to severe, or fatal. This study aimed to analyze the symptomatic and clinical characteristics of study participants based on the medical records of participants hospitalized with COVID-19 in Uzbekistan.

Methods:

We collected all data from medical records of COVID-19 confirmed patients in 19 hospitals from 13 regions of Uzbekistan between March 15 and April 30. We selected 1,030 patients discharged from the hospitals after COVID-19 treatment as study participants, excluding those with missing data. Further, we collected demographics, symptoms, clinical outcomes, and treatment data through medical records.

Results:

More than half (57.6%) of confirmed cases of COVID-19 were males, and the median age was 36.0 years. The most frequent symptoms at the first inspection on hospital admission of all patients were fatigue (59.7%), dry cough (54.1%), pharyngalgia (31.6%), headache (20.6%), and anorexia (12.5%). Compared to the oldest group, the youngest group showed a lower frequency of symptoms. About half of the group aged 18-49 years reported that they came from abroad. One-fifth of patients in group 50-84 received oxygen support, while no patients in group aged 0-17 years received oxygen support. About two-thirds of the participants from intensive care unit (ICU) came from abroad, whereas 42.1% of the non-ICU group returned from other countries. Regarding symptoms, 16.9% of the patients in the ICU group were asymptomatic, while 5.8% in the non-ICU group were asymptomatic.

Conclusion:

This study suggests that the medical delivery system and resource distribution need to be implemented based on clinical characteristics by age and severity to delay and effectively respond to the spread of infections in the future. This study analyzed symptoms of COVID-19 patients across Uzbekistan, which is useful as primary data for policies on COVID-19 in Uzbekistan.

Keywords:

COVID-19 Characteristics SARS-CoV-2 Uzbekistan

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