Related Experiment Video
Updated: Nov 29, 2025

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
Published on: January 12, 2019
Innovative use of increasing the width of attached gingiva using chorion membrane along with platelet rich fibrin
Shaila Kothiwale1, Jyoti Ajbani2
1Department of Periodontics, KLEs V. K. Institute of Dental Sciences, KAHER, Belagavi, Karnataka, 590010, India. shailakothiwale2000@yahoo.co.in.
Abstract:
Width of attached gingiva plays an important role in maintaining periodontal health, provides stabilization of the gingival margin against frictional forces and aids in dissipating physiological forces exerted by the muscular fibers of the alveolar mucosa on the gingival tissues. Inadequate width of attached gingiva leads to attachment loss, soft tissue recession, and impedes oral hygiene measures. Hence, procedures using autografts and allografts have been proposed to augment the attached gingiva. Allografts like chorionic membrane (CM) are known to enhance release of growth factors, promote neovascularization, healing and enhance biotype. To assess the efficacy of CM in increasing the width of attached gingiva, vestibular depth and gingival thickness. Fifteen patients with inadequate attached gingival width were included in the study. Patients were randomly allocated to each group: Control group, CM group and CM + platelet rich fibrin (PRF) group. Attached gingiva width, vestibular depth, and gingival thickness were measured at baseline and 4 weeks post procedure. The control, CM and CM + PRF groups showed an increase in all parameters from baseline to 4 weeks. The increase in the attached gingiva (p = 0.042) width, vestibular depth (p = 0.043) and gingival thickness (p = 0.034) were statistically significant at 4 weeks for CM group and CM + PRF group respectively. The CM + PRF group showed better results compared to other groups. CM and PRF can be effectively incorporated to increase the width of attached gingiva and depth of vestibule.

