Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

4.4K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.4K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

3.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
3.9K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

2.6K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.6K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

192
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
192
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

1.7K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.7K
Vitamins01:30

Vitamins

1.9K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Roles of Ras Homolog Guanosine Triphosphate Phosphohydrolases in Adipocyte Differentiation, Insulin Signaling, and Lipid Droplet Dynamics.

The Journal of nutrition·2026
Same author

Advances in modeling memory decline: A critical overview of current animal and human paradigms.

Ageing research reviews·2026
Same author

An Association of Elevated Blood Vitamin A Level and Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease in Humans.

The Journal of nutrition·2026
Same author

Activating plasmonic catalysis through light-mediated steady-state spin modulation.

Nature communications·2026
Same author

Quantitative lipidomic analysis reveals glycine betaine-hot water treatments preserve banana peel integrity under chilling stress.

Food chemistry·2026
Same author

Synchronizing carrier extraction and dielectric coupling in a hierarchical homometallic plasmonic catalyst for light-driven nitrate reduction.

Nanoscale·2026

Related Experiment Video

Updated: Nov 29, 2025

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.4K

Vitamin A and Diabetes.

Yan Zhang1, Tiannan Wang2, Xinge Hu2

  • 1Department of Gastroenterology, Affiliated Puren Hospital of Wuhan University of Science and Technology, Wuhan, China.

Journal of Medicinal Food
|November 24, 2020
PubMed
Summary

Vitamin A (VA) plays a role in glucose and lipid metabolism, impacting diabetes. Research indicates type 1 diabetes lowers blood VA levels, while its effect on type 2 diabetes remains unclear, necessitating further study.

Keywords:
diabetesdiabetic nephropathydiabetic neuropathydiabetic retinopathyretinoic acidvitamin Awound healing

More Related Videos

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.4K
Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature
10:07

Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature

Published on: December 26, 2017

13.7K

Related Experiment Videos

Last Updated: Nov 29, 2025

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.4K
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.4K
Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature
10:07

Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature

Published on: December 26, 2017

13.7K

Area of Science:

  • Endocrinology and Metabolism
  • Nutritional Science

Background:

  • Vitamin A (VA), a vital micronutrient, is increasingly recognized for its role in regulating glucose and lipid metabolism.
  • Diabetes mellitus is a complex metabolic disorder where understanding the interplay with micronutrients like VA is crucial.

Purpose of the Study:

  • To review and synthesize current knowledge on the relationship between vitamin A and its metabolites in the context of diabetes.
  • To highlight the impact of diabetes on vitamin A metabolism and the potential therapeutic roles of VA in diabetes management.

Main Methods:

  • A comprehensive literature search was conducted using PubMed with keywords related to diabetes and vitamin A or its metabolites.
  • Articles published up to April 2020 were retrieved and analyzed to summarize existing research findings.

Main Results:

  • Type 1 diabetes is associated with reduced blood vitamin A levels in humans and animals, alongside increased hepatic VA storage in experimental models.
  • The reciprocal relationship between type 2 diabetes, vitamin A intake, and blood VA levels is currently uncertain.
  • Retinoic acid, an active vitamin A metabolite, shows potential in managing diabetic complications.

Conclusions:

  • Diabetes development is linked to alterations in vitamin A metabolism.
  • Further rigorous clinical and laboratory research is essential to elucidate the precise effects of diabetes on VA metabolism.
  • The role of vitamin A in both the pathogenesis and treatment of diabetes requires continued investigation.