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Related Concept Videos

Alzheimer's Disease: Overview01:26

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
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Neural Regulation01:37

Neural Regulation

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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Related Experiment Video

Updated: Nov 28, 2025

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
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[Advanced Disease Situations with Organic Brain Changes].

Susanne Hedbom1, Sereina Catschegn1

  • 1Kompetenzzentrum für Palliative Pflege und Medizin, Zürcher Lighthouse.

Praxis
|November 25, 2020
PubMed
Summary

Patients with organic brain changes in palliative care face complex neurological and psychological symptoms. Effective management requires advanced care planning and a supportive environment for optimal quality of life.

Keywords:
Best Supportive CarePalliative CarePalliative carePalliativmedizinSoins palliatifsaltérations organiques du cerveaubest supportive carehirnorganische Veränderungenlong-term facilitiesmeilleurs soins de soutienmédicine palliativeorganic brain changespalliative medicinespezialisierte Langzeiteinrichtungstructures spécialisées de soins palliatifs

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Area of Science:

  • Palliative Care
  • Neurology
  • Psychology

Background:

  • Most patients in specialized long-term palliative care facilities exhibit organic brain changes.
  • These conditions present with intricate neurological and psychological symptoms, demanding significant patient care and specific environmental settings.

Purpose of the Study:

  • To address the challenges of advanced care planning in physical, psychosocial, and existential domains for patients with organic brain changes.
  • To highlight the importance of a structured, calm environment and interprofessional collaboration in managing these complex cases.

Main Methods:

  • Review of general treatment principles for diseases associated with neurological and psychological symptoms.
  • Emphasis on environmental optimization and interprofessional cooperation in palliative care settings.

Main Results:

  • Organic brain changes are prevalent in long-term palliative care, presenting complex symptom clusters.
  • Structured environments and collaborative care are crucial for managing these patients.

Conclusions:

  • Advanced care planning and a supportive environment are essential for enhancing the quality of life for palliative care patients with organic brain changes.
  • Tailored treatment strategies based on specific symptoms are vital for effective patient management.