Related Experiment Video
Updated: Nov 28, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Nonsteroidal Anti-Inflammatory Drugs: Updates on Dosage Formulations and Adverse Effects
Kathleen Cunningham1,2,3, Danielle M Candelario1,2,3, Lauren B Angelo1,2,3
1Kathleen Cunningham, PharmD, BCPS, is Assistant Professor, Pharmacy Practice, College of Pharmacy, Rosalind Franklin University of Medicine & Science, North Chicago, IL; Clinical Pharmacist, Solid Organ Transplant, and Residency Program Director, PGY2 Solid Organ Transplant, Northwestern Memorial Hospital, Chicago, IL.
Nonsteroidal anti-inflammatory drugs (NSAIDs) offer benefits but pose risks to the gastrointestinal, cardiovascular, bone, and renal systems. This review updates on NSAID formulations, availability, and adverse effects, focusing on nonaspirin options.
Area of Science:
- Pharmacology
- Internal Medicine
Background:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely prescribed and available over-the-counter.
- Their therapeutic efficacy is well-established for various conditions.
- However, significant concerns exist regarding their impact on multiple organ systems.
Purpose of the Study:
- To provide an updated overview of NSAID dosage formulations and product availability.
- To highlight key adverse effects and warnings associated with NSAID use.
- To emphasize the safety profile of nonaspirin NSAIDs.
Main Methods:
- Literature review of current NSAID products.
- Analysis of reported adverse events and warnings.
- Focus on nonaspirin NSAID characteristics.
Main Results:
- NSAIDs are available in diverse formulations for varied patient needs.
- Adverse effects impact gastrointestinal, cardiovascular, bone, and renal physiology.
- Specific warnings are crucial for safe and effective NSAID utilization.
Conclusions:
- Understanding NSAID formulations and risks is essential for clinicians and patients.
- Careful consideration of adverse effects guides appropriate NSAID selection and monitoring.
- Nonaspirin NSAIDs require specific attention regarding their safety profile.
Related Concept Videos
Drugs for Treatment of Ulcerative Colitis in IBD
FDA Approved Drugs: Changes to Approved Drugs
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents
Non-steroidal anti-inflammatory drugs (NSAIDs) can induce peptic ulcers by inhibiting cyclooxygenase, decreasing...
Dosage Regimen: Individualization

