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Related Experiment Videos

Ultrasonically guided direct umbilical cord blood sampling.

E Amon1, J V Dacus, B C Mabie

  • 1Department of Obstetrics and Gynecology, University of Tennessee, Memphis.

The Journal of Reproductive Medicine
|November 1, 1987
PubMed
Summary

Ultrasonically guided umbilical cord blood sampling, or funicentesis, enables swift fetal disease diagnosis. This method identified a chromosomal abnormality in one fetus, highlighting its diagnostic potential.

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Area of Science:

  • Perinatology
  • Fetal Medicine
  • Genetics

Background:

  • Prenatal diagnosis is crucial for managing fetal conditions.
  • Umbilical cord blood sampling offers a route for fetal testing.
  • Ultrasonography enhances the precision of invasive procedures.

Observation:

  • Three fetuses underwent ultrasonically guided umbilical cord blood sampling.
  • The procedure aimed to diagnose fetal viral infections and other diseases.
  • Karyotyping was performed for rapid genetic analysis.

Findings:

  • One of the three fetuses exhibited a chromosomal abnormality, specifically trisomy 18.
  • No viral infections were detected in any of the studied fetuses.
  • Funicentesis proved effective for karyotyping and disease detection.

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Implications:

  • Ultrasonically guided funicentesis is a valuable tool for prenatal diagnosis.
  • Early identification of chromosomal abnormalities like trisomy 18 aids in management.
  • The technique's utility extends to diagnosing various fetal diseases beyond infections.