Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Combined modality therapy in malignant lymphomas.

E Glatein, S S Donaldson, S A Rosenberg

    Cancer Treatment Reports
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pernicious anemia and susceptibility to gastric neoplasms.

    The Journal of laboratory and clinical medicine·2010
    Same author

    Pernicious anemia and tumors of the stomach.

    Journal of the National Cancer Institute·2010
    Same author

    Getting the right blood to the right patient: the contribution of near-miss event reporting and barrier analysis.

    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine·2005
    Same author

    Event reporting systems: MERS-TM, surveillance--seeing and using the data below the waterline.

    Developments in biologicals·2005
    Same author

    Organization of event reporting data for sense making and system improvement.

    Quality & safety in health care·2003
    Same author

    Reporting of near-miss events for transfusion medicine: improving transfusion safety.

    Transfusion·2001

    The Rappaport classification system remains valuable for non-Hodgkin's lymphoma (NHL) staging. Treatment strategies involving radiotherapy and chemotherapy show varying efficacy based on NHL type and stage.

    Area of Science:

    • Hematology
    • Oncology
    • Pathology

    Background:

    • Treatment for non-Hodgkin's lymphomas (NHL) is debated.
    • The Rappaport classification system distinguishes between favorable (nodular/follicular) and unfavorable (diffuse) NHL.
    • Despite challenges, no newer classification has surpassed the Rappaport system.

    Purpose of the Study:

    • To review the roles of radiotherapy and chemotherapy in NHL treatment.
    • To evaluate the effectiveness of combined modality approaches.
    • To highlight the importance of expert hematopathology in NHL studies.

    Main Methods:

    • Review of existing literature on NHL treatment modalities.
    • Analysis of randomized studies on combined radiotherapy and chemotherapy.

    Related Experiment Videos

  • Assessment of treatment outcomes based on NHL histology and stage.

    • Main Results:

    • Radiotherapy is effective for controlling detectable NHL disease.
    • Chemotherapy is primarily used for eradicating microscopic tumor foci.
    • Adjuvant chemotherapy shows no definitive benefit in early-stage unfavorable NHL.
    • Adjuvant radiotherapy may improve outcomes in advanced-stage unfavorable NHL.
    • Aggressive regimens offer no clear advantage over conservative ones for favorable, advanced NHL.

    Conclusions:

    • Expert hematopathologic interpretation is crucial for all non-Hodgkin's lymphoma studies.
    • Treatment decisions should consider NHL histology, stage, and modality effectiveness.
    • Further research may refine current treatment paradigms for NHL.