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Updated: Nov 28, 2025

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
Human papillomavirus genotyping as a tool for cervical cancer prevention: from commercially available human
Tauana Christina Dias1, Adhemar Longatto-Filho1,2,3,4, Nathalia C Campanella1
1Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo, Brazil.
Abstract:
The biological importance of human papillomavirus (HPV) in the field of medicine - related to cervical carcinogenesis - has been extensively reported in the last decades. For the first time, a direct correlation between cause and effect to explain a cancer development was completely achieved in medical research. Consequently, the Nobel Prize was awarded to HZ Hausen in 2008 for his efforts to understand the effects of persistent infection of oncogenic types of HPV and malignancy transformation. The aim of the present review was to summarize the principal elements of HPV characteristics and their importance in oncology.

