A Pilot Comparison of High- Versus Low-Tech Palatability Assessment Tools in Young Children

Susan M Abdel-Rahman1,2, Shasha Bai3, Patricia A Porter-Gill4

  • 1Division of Pediatric Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO, 64108, USA. srahman@cmh.edu.

Paediatric Drugs
|November 25, 2020
PubMed

Insights

Pediatric medication taste is a barrier to adherence. This study found hedonic scales, particularly TASTY, are more reliable than facial recognition for assessing children's taste perception.

Area of Science:

  • Pediatric Pharmacology
  • Sensory Science
  • Clinical Assessment

Background:

  • Medication refusal in children is often due to unpleasant taste, impacting treatment adherence and outcomes.
  • Standardized methods for evaluating taste perception in young children are lacking.
  • This study investigates novel methods for assessing pediatric taste responses.

Purpose of the Study:

  • To compare the efficacy of facial recognition technology with established hedonic visual scales in assessing pediatric taste perception.
  • To identify reliable methods for evaluating the palatability of medications in children aged 3-7 years.

Main Methods:

  • A double-blind, randomized study involving 12 children (3-7 years) evaluating prednisone (bitter), simple syrup (sweet), and water (neutral).
  • Facial expression and intensity were recorded using Noldus FaceReader 7 software.
  • Taste perception was assessed using 5-point Sjövall and 5- and 3-point TASTY hedonic scales, alongside simple participant questions.

Main Results:

  • All three hedonic scales demonstrated similar tracking for different taste profiles, with high correlations between scale variations.
  • Facial recognition technology was less reliable, failing to effectively differentiate positive and negative taste responses.
  • Hedonic scales showed greater reliability in assessing children's taste responses compared to facial recognition.

Conclusions:

  • The TASTY scales (3- and 5-point) show significant promise for assessing medication palatability in pediatric clinical settings.
  • Reliable taste assessment methods are crucial for improving medication adherence and therapeutic outcomes in children.
  • Further research should focus on validating and implementing these hedonic scales in clinical practice.
Abstract

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