Related Experiment Video
Updated: Nov 28, 2025

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Frailty in community-dwelling older people: comparing screening instruments
Jair Almeida Carneiro1, Andressa Samantha Oliveira Souza2, Luciana Colares Maia3
1Universidade Estadual de Montes Claros. Centro de Ciências Biológicas e da Saúde. Departamento de Saúde Mental e Saúde Coletiva. Montes Claros, MG, Brasil.
The Edmonton Frail Scale (EFS) and Clinical-Functional Vulnerability Index-20 (CFVI-20) show moderate agreement in assessing frailty in older Brazilians, but prevalence rates differ, highlighting the need for standardized tools.
Area of Science:
- Gerontology
- Public Health
- Epidemiology
Background:
- Frailty is a significant geriatric condition impacting community-dwelling older adults.
- Accurate assessment tools are crucial for identifying individuals at risk and implementing timely interventions.
- Comparing existing frailty assessment instruments is essential for clinical practice and research.
Purpose of the Study:
- To compare the Edmonton Frail Scale (EFS) and Clinical-Functional Vulnerability Index-20 (CFVI-20) in community-dwelling older adults in Brazil.
- To evaluate the agreement and correlation between EFS and CFVI-20.
- To identify variables associated with frailty and clinical-functional vulnerability.
Main Methods:
- A cross-sectional study nested within a population-based household cohort.
- Kappa statistic and Pearson's correlation coefficient were used to assess agreement and correlation.
- Multiple Poisson regression analysis identified factors associated with frailty.
Main Results:
- Moderate agreement (Kappa=0.599) and strong positive correlation (r=0.755) were found between EFS and CFVI-20.
- Prevalence of frailty was 28.2% by EFS and 19.5% by CFVI-20.
- Age (≥80 years), stroke history, polypharmacy, poor self-perceived health, falls, and hospitalizations were associated with frailty by both instruments.
Conclusions:
- While EFS and CFVI-20 show moderate agreement and strong correlation, their prevalence estimates for frailty differ.
- Specific factors like education, osteoarticular disease, weight loss, and caregiver status showed differential associations with frailty depending on the instrument.
- Standardization of frailty assessment instruments is necessary for community-dwelling older populations.
More Related Videos
05:53Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
07:27Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
Related Concept Videos
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Pharmacodynamics in Geriatric Patients: Effects of Age