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Updated: Nov 28, 2025
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Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging
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Optical coherence tomography (OCT) in neuro-ophthalmology
Neda Minakaran1, Emanuel R de Carvalho2,3, Axel Petzold2,4,5
1Moorfields Eye Hospital NHS Foundation Trust, London, UK. neda.minakaran@gmail.com.
Eye (London, England)
|November 26, 2020
Summary
Optical coherence tomography (OCT) aids in diagnosing neuro-ophthalmic conditions by analyzing the optic nerve and retina. This review covers OCT
Area of Science:
- Ophthalmology and Neuroscience
Background:
- Optical coherence tomography (OCT) is a crucial non-invasive imaging technology for neuro-ophthalmic conditions.
- OCT enables detailed characterization of the optic nerve head, retinal nerve fiber layer, and macular cellular layers, including the ganglion cell layer.
Purpose of the Study:
- To review the technical aspects and applications of OCT in neuro-ophthalmology.
- To discuss potential pitfalls and emerging OCT angiography uses in managing neuro-ophthalmic diseases.
Main Methods:
- Review of existing literature and clinical applications of OCT in neuro-ophthalmology.
- Discussion of OCT's capabilities in qualitative and quantitative assessment of optic nerve diseases.
Main Results:
- OCT provides valuable insights into optic nerve head and retinal structure.
- The technology aids in the assessment of various optic neuropathies and related conditions.
Conclusions:
- OCT is increasingly vital for diagnosing and managing neuro-ophthalmic disorders.
- Emerging OCT angiography techniques show promise for expanded clinical utility.
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