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Related Concept Videos

Epigenetic Regulation01:37

Epigenetic Regulation

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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Epigenetic Regulation01:46

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Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Histone Modification02:32

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex.
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Gene-Environment Interactions01:20

Gene-Environment Interactions

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Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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Author Spotlight: Enhancements in Gene Expression Regulation Research
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Communicating science: epigenetics in the spotlight.

Stephanie O M Dyke1,2, Catherine A Ennis3,4, Yann Joly1

  • 1Faculty of Medicine, Centre of Genomics and Policy, McGill University, Montreal (Quebec), H3A 0G1, Canada.

Environmental Epigenetics
|November 26, 2020
PubMed
Summary
This summary is machine-generated.

Media coverage of epigenetics often overstates findings due to experimental limits. Standardized evaluation criteria and researcher-provided press kits can improve accurate reporting of epigenetic science.

Keywords:
epigeneticspublic understanding of sciencescience communication

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Area of Science:

  • Epigenetics
  • Media Studies
  • Science Communication

Background:

  • Public interest in epigenetics is high.
  • Understanding media portrayal is crucial for public perception of epigenetic science.

Purpose of the Study:

  • Analyze media representations of epigenetics in North American, European, and Asian newspapers.
  • Evaluate the policy focus and balance of epigenetic science reporting.
  • Identify shortcomings in media portrayal and their causes.

Main Methods:

  • Content analysis of national newspaper coverage.
  • Case study analysis of scientific evidence and its translation in media.
  • Qualitative assessment of recurring themes and policy messages.

Main Results:

  • Recurring themes included individual and societal responsibilities related to epigenetics.
  • Shortcomings were identified in the media's portrayal of epigenetic science.
  • Epigenetic study results are often overstated in academic publications due to experimental limitations.

Conclusions:

  • Overstatement of epigenetic research findings contributes to inaccurate media portrayals.
  • Standardized criteria for evaluating epigenetic studies are needed.
  • A Press Kit template can help researchers develop accurate and balanced press releases for broader audiences.