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Updated: Nov 28, 2025

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
Published on: May 14, 2020
Noah B Bonnheim1, Douglas W Van Citters2, Michael D Ries3
1Department of Mechanical Engineering, University of California, Berkeley, CA.
This study examined the surfaces of retrieved hip and knee implants made from oxidized zirconium (OxZr) and cobalt-chromium (CoCr). Researchers found that OxZr implants generally maintain a smooth surface unless they are removed due to hip dislocation. When dislocated, OxZr components showed significant damage, including loss of the ceramic surface layer and increased roughness. In contrast, CoCr implants remained smooth even after dislocation. The findings suggest that OxZr is more sensitive to dislocation and may not be the best choice for patients at high risk of this complication. These results could influence material selection for joint replacements.
Area of Science:
Background:
Oxidized zirconium has been proposed as a material for hip and knee implants due to its ceramic-like wear resistance and metal-like strength. However, its performance compared to traditional alloys remains uncertain. Some studies suggest OxZr does not offer better wear or outcomes than cobalt-chromium. A concern is the potential for surface layer damage, which could affect implant longevity. Prior research has shown that ceramic coatings can degrade under stress. The extent of this degradation and its clinical consequences are not well defined. This uncertainty has driven further investigation into OxZr's behavior in the body. Understanding how OxZr responds to mechanical failure is important for implant design. Surface roughness and material exposure may influence wear and patient outcomes.
Purpose Of The Study:
The goal of this study was to assess the in vivo performance of oxidized zirconium implants, focusing on surface integrity. Researchers aimed to determine if OxZr components maintain a smooth surface under normal use. They also wanted to evaluate how dislocation affects OxZr surfaces compared to cobalt-chromium. The study sought to measure surface roughness and identify signs of ceramic layer loss. By comparing retrieved implants, the team hoped to clarify OxZr's behavior after mechanical failure. Dislocation is a known complication in hip implants, so its impact on OxZr was a key focus. The researchers also wanted to understand if OxZr is more vulnerable to damage than traditional materials. This information could help guide material selection for joint replacements.
Main Methods:
The study analyzed 94 retrieved femoral components from total hip and knee arthroplasties. These included 43 OxZr TKA, 21 OxZr THA, and 30 CoCr THA implants. Surface characteristics were assessed using optical microscopy, non-contact profilometry, and scanning electron microscopy. Researchers measured surface roughness using Sa values to compare materials. They also looked for signs of ceramic layer effacement and metal exposure. Components revised for dislocation were compared to those removed for other reasons. The study focused on differences in surface damage between OxZr and CoCr. Data were analyzed statistically to determine significance of findings.
Main Results:
OxZr components generally maintained a smooth surface unless revised for dislocation. Three of four OxZr femoral heads removed after dislocation showed severe damage. These included large areas of ceramic layer loss and exposed metal. The damaged OxZr surfaces were 23-32 times rougher than undamaged controls. When compared to CoCr, dislocated OxZr heads were much rougher (Sa 0.431 vs. 0.020 μm). CoCr dislocated heads had low roughness (Sa 0.020 vs. 0.008 μm). Surface roughening was not typical for CoCr regardless of dislocation status. The findings suggest OxZr is more sensitive to dislocation than CoCr.
Conclusions:
Oxidized zirconium components retain a smooth surface under normal conditions. However, dislocation causes significant damage to OxZr surfaces. The ceramic layer is lost, exposing the metal substrate and increasing roughness. This roughening is much more pronounced in OxZr than in cobalt-chromium. The study found that OxZr is less tolerant of dislocation events. Dislocated OxZr heads were substantially rougher than CoCr dislocated heads. The authors suggest that OxZr may not be the best choice for patients at high risk of dislocation. These findings support the need for careful material selection in implant design.
Three of four OxZr femoral heads revised for dislocation showed severe damage, including ceramic layer loss and metal exposure.
Researchers used non-contact profilometry to measure Sa values, comparing OxZr and CoCr components.
Effacement exposes the metal substrate, increasing surface roughness and potentially affecting implant wear and longevity.
Dislocated OxZr heads were 23-32 times rougher than undamaged OxZr and much rougher than dislocated CoCr heads.
Sa values quantify surface roughness, showing that OxZr dislocated heads had Sa 0.431 μm, compared to 0.020 μm for CoCr dislocated heads.
The authors suggest OxZr may not be ideal for patients at high risk of dislocation due to its sensitivity to mechanical failure.