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Updated: Nov 28, 2025

Trace Fear Conditioning in Mice
Published on: March 20, 2014
Gaëtan Mertens1, Yannick Boddez2, Angelos-Miltiadis Krypotos3
1Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands; Department of Clinical Psychology, Utrecht University, Utrecht, the Netherlands.
Instructions about the conditioned stimulus-unconditioned stimulus (CS-US) contingency facilitate human fear conditioning and awareness. Providing or instructing participants to discover the CS-US contingency significantly enhances fear acquisition and reversal compared to no instructions.
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