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Updated: Nov 28, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Outcomes of Carotid Artery Replacement With Total Arch Reconstruction for Type A Aortic Dissection
Ibrahim Sultan1, Edgar Aranda-Michel2, Valentino Bianco2
1Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Insights
Concomitant carotid artery replacement during total arch repair for acute type A aortic dissection is safe. This procedure effectively addresses cerebral malperfusion and carotid dissection without impacting long-term survival or stroke rates.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Thoracic Surgery
Background:
- Acute type A aortic dissection (TAAD) poses significant risks, particularly cerebral malperfusion and carotid artery dissection.
- Outcomes data for combined carotid artery replacement with total arch repair in TAAD patients are limited.
Purpose of the Study:
- To evaluate the safety and efficacy of concomitant carotid artery replacement during total arch replacement for acute TAAD.
- To compare outcomes between patients undergoing conventional total arch replacement and those receiving additional carotid artery repair.
Main Methods:
- Retrospective analysis of 161 patients undergoing total arch replacement for acute TAAD (2007-2018).
- Comparison of 111 patients with conventional reconstruction versus 50 patients with concomitant carotid artery replacement.
- Kaplan-Meier survival estimates and Cox regression analysis for mortality predictors.
Main Results:
- The carotid replacement cohort had higher rates of preoperative cerebral malperfusion (48%) and stroke (28%) compared to the conventional group.
- No significant difference in 30-day, 1-year, or 5-year mortality between the two groups.
- Postoperative stroke rates were similar (0% vs. 4.5%), with a trend towards fewer strokes in the carotid replacement group.
Conclusions:
- Concomitant carotid artery replacement is a safe and feasible strategy for managing cerebral malperfusion and carotid dissection in TAAD.
- This approach does not compromise long-term survival or increase postoperative stroke risk compared to conventional total arch replacement.
Background:
Cerebral malperfusion and carotid artery dissection in patients with acute type A aortic dissections (TAAD) carry high morbidity and mortality. There are limited data on outcomes of concomitant carotid artery replacement with total arch replacement in the setting of TAAD.
Methods:
All patients with acute TAAD who underwent a total arch replacement between 2007 and 2018 were included. Data were retrospectively collected from a prospectively maintained database. Baselines variables were compared, and Kaplan-Meier estimates were used for long-term survival. Cox multivariable regression analysis was used to identify predictors of mortality.
Results:
A total of 161 patients underwent total arch replacement for acute TAAD. Of these, 111 underwent conventional total arch reconstruction, and 50 had a concomitant carotid artery replacement. Baseline characteristics were similar between both cohorts apart from the carotid replacement cohort having a higher rate of preoperative cerebral malperfusion (48% vs 10.81%, P < .01) and preoperative stroke (28% vs 11.71%, P = .02). There was no difference in (operative) 30-day mortality between the carotid replacement and conventional total arch replacement groups (22% vs 18.9%, P = .81), 1-year mortality (28% vs 27.9%, P = .99), or 5-year mortality (32% vs 29.7%, P = .917). Postoperative stroke was 0% vs 4.5% (P = .301) for the carotid vs conventional total arch replacement cohort.
Conclusions:
Concomitant carotid artery replacement is a feasible and safe technique to address perioperative cerebral malperfusion, carotid dissection, and neurologic dysfunction associated with carotid artery dissection, with no difference in long-term survival or postoperative stroke when compared with conventional total arch replacement.
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