Related Experiment Video
Updated: Nov 28, 2025

Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy
Published on: September 25, 2017
Cardiac Lipomatosis: A Rare Form of Left Ventricular Hypertrophy
Mateusz Śpiewak1, Mariusz Kłopotowski2, Łukasz A Małek3
1Magnetic Resonance Unit, Department of Radiology, National Institute of Cardiology, Warsaw, Poland.
Insights
A 30-year-old female presented with abnormal ECG findings of left ventricular hypertrophy. Cardiac imaging revealed atypical wall thickening with fat-like signal intensity, showing no progression over time.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Cardiac MRI
Background:
- Left ventricular hypertrophy (LVH) is a common finding on electrocardiography (ECG).
- Atypical patterns of LVH can present diagnostic challenges.
- Cardiac magnetic resonance (CMR) is crucial for detailed cardiac structure assessment.
Observation:
- A 30-year-old female with asymptomatic LVH on ECG.
- Echocardiography showed heterogeneous echogenicity in left ventricular walls.
- Cardiac MRI revealed marked, symmetrical ventricular wall thickening.
Findings:
- The thickened ventricular walls demonstrated increased signal intensity on MRI, mimicking subcutaneous fat.
- No progression of left ventricular hypertrophy was observed on follow-up imaging.
- This suggests a potential infiltrative or storage process.
Implications:
- This case highlights the utility of advanced cardiac imaging in diagnosing rare causes of left ventricular hypertrophy.
- Understanding atypical MRI signal characteristics is vital for accurate diagnosis.
- Further investigation may be warranted to determine the underlying etiology.
Abstract:
A 30-year-old female patient was referred to our centre due to an abnormal electrocardiography showing left ventricular hypertrophy. The physical examination was normal, and the patient was asymptomatic. Echocardiography was performed, revealing an atypical pattern of left ventricular hypertrophy with heterogeneous echogenicity of the left ventricular walls. A cardiac magnetic resonance examination revealed marked thickening of the interventricular septum and left and right ventricular walls. The signal intensity of the thickened ventricular walls was increased and was similar to that of subcutaneous fat. Follow-up echocardiography and cardiac magnetic resonance showed no progression of left ventricular hypertrophy.
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy I: Introduction and Classification
Cardiomyopathy V: Interprofessional Care
Mitral Stenosis I: Introduction
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy

